The Strain is a high-concept thriller that tells the story of Dr. Ephraim Goodweather, the head of the Center for Disease Control Canary Team in New York City. He and his team are called upon to investigate a mysterious viral outbreak with hallmarks of an ancient and evil strain of vampirism. As the strain spreads, Goodweather, his team, and an assembly of everyday New Yorkers wage war for the fate of humanity itself.
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The Last Stand 04x10
The team is forced to retreat, and Quinlan and Vasily come up with a plan to use the nuke to destroy the Master once and for all.
The Traitor 04x09
The team threatens Selah to get leverage against Desai. Meanwhile, Eph tries to determine if Zack is working for the Master or not, while Gus goes to recover the nuke.
Before he has Quinlan kill him, Abraham tells the others how to defeat the Master. They begin by assaulting the Partnership facility and capturing Desai. Meanwhile, the Master sends Zack on a special mission.
Eph reunites with Abraham and Dutch, bringing Alex along with him. His health failing, Setrakian ignores Eph's warnings, pushing himself to the limit in his quest for victory and revenge. Fet and Quinlan race back to Manhattan. Meanwhile, Gus decides to help the resistance, but Creem goes to the Master with valuable information. Later, the Master seals off the city and prepares to eliminate them all.
Tainted Love 04x06
Roman takes the others to meet with an old friend who can provide them with a plane and get the warhead to New York. Meanwhile, Zack learns a painful lesson about love.
Belly of the Beast 04x05
While Vasiliy and Quinlan acquire the nuclear pit from the strigoi convoy, Eph and Alex head for New Horizons to discover it's secret. Meanwhile, Dutch leads a rebellion and finds Abraham, while in the past, Quinlan finds a moment of happiness.
New Horizons 04x04
Desai forces Dutch to help him calm down a woman undergoing C-section. Meanwhile, the underground takes a heavy blow and Eph and Alex learn of New Horizons.
One Shot 04x03
While Vasiliy and Quinlan try to obtain a nuclear warhead, Eph leads a strike against the strigoi in Philadelphia... alerting the Master and Eichhorst to his presence. Meanwhile, Zack makes a new friend.
The Blood Tax 04x02
The fates of Gus and Dutch are revealed, while Eph continues to help Alex and her brother.
The Worm Turns 04x01
Nine months after the warhead detonated in New York, the strigoi have formed a "partnership" with the humans, offering free medical care in return for blood donations. Eph is in Philadelphia trying to make a life for himself on the fringes, while Vasily and Quinlan try to acquire a nuclear warhead. Meanwhile, the Master plans to raise Zack as his next host body.