Lincoln Burrows is currently on death row and scheduled to die in a few months for an assassination his younger brother Michael is convinced he did not commit. With no other options and time winding down, Michael takes drastic measures to get himself incarcerated alongside his brother in Fox River State Penitentiary. Once he's inside, Michael - a structural engineer with the blueprints for the prison - begins to execute an elaborate plan to break Lincoln out and prove him innocent. When Michael arrives at Fox River State Penitentiary, he meets the prison denizens who will, unknowingly, help in his escape plans - his cellmate, the lovelorn Sucre; beautiful prison doctor Dr. Sara Tancredi, who happens to be the governor's daughter; former mob boss John Abruzzi; and Warden Henry Pope. Meanwhile, outside the prison walls, the brothers' childhood friend and Lincoln's lost love, attorney Veronica Donovan, works within the law to free them; Lincoln's teenage son LJ may be going down a path similar to his convicted father's; and Secret Service Agent Paul Kellerman's investigation into Lincoln's case proves that there may be a national conspiracy.
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Behind the Eyes 05x09
Dangerous threats keep Michael and Lincoln fighting to protect Sara and Mike. Meanwhile, Poseidon continues to try and outsmart Michael and the rest of the gang, which leads them to the ultimate showdown, and not everyone makes it out alive.
When Sara and her son's safety is threatened, Michael and Lincoln recruit the help of Sheba and C-Note to try and catch Poseidon. Meanwhile, Whip goes on a separate mission and T-Bag reveals a secret.
Wine-Dark Sea 05x07
Sara becomes fearful of her family's safety when she discovers the real reason that Michael faked his own death. In the meantime, Michael and Lincoln continue to try find a way home with the help of Sucre, and the real identity of Poseidon is revealed.
As Michael, Lincoln and the remaining Ogygia gang try to escape Yemen, they find themselves racing though the desert from a vengeful Cyclops. Meanwhile, A&W and Van Gogh question their roles as their pursuit of the escapees leads them to...Graceland.
Lincoln becomes frustrated as he tries to understand what really happened to Michael. C-Note has a new escape plan, but fears it will not be executed quickly enough, as Cyclops is trailing closely behind. Meanwhile, Sara struggles with the idea that Michael may be alive.
The Prisoner's Dilemma 05x04
Michael, Whip and Ja make their last attempt to break from Ogygia, but must make a deal with the devil to do so. Lincoln races against the clock to help with the escape, as T-Bag meets with Kellerman to gather more info on Michael's resurrection.
The Liar 05x03
When T-Bag ambushes Sara, he warns her that two of Poseidon's henchmen, Van Gogh and A&W, may be following her. Meanwhile, Lincoln attempts to retrieve his confiscated passport to escape Yemen, and Michael plans his next move.
Kaniel Outis 05x02
As Lincoln and C-Note search for the "Sheik of Light," Michael and his cellmate, Whip, attempt an escape from Ogygia. Meanwhile, Sara's investigation into Michael's reappearance leads her to the state department and an uneasy reunion with Paul Kellerman.
In the season premiere clues surface that suggest a previously thought-to-be-dead Michael may be alive. Lincoln and Sara, Michael's wife until he was presumed dead, reunite to engineer the series' biggest escape ever, as three of Fox River State Penitentiary's most notorious escapees, Sucre, T-Bag and C-Note, are pulled back into the action.
Killing Your Number 04x22
After the general catches the brothers and raises the stakes by abducting more of their relatives, Michael escapes with Scylla.